研究業績（2025年）

英文原著論文・英文総説

• First clinical implementation of dynamic tumour-tracking volumetric modulated arc therapy with a gimbal-mounted linac: short delivery time and high precision. Kishi N, Nakamura M, Hirashima H, Adachi T, Yoneyama M, Kawata K, Kishigami Y, Ogata T, Murakami T, Iizuka Y, Seno H, Mizowaki T. J Radiat Res. in press, 2025
• Hierarchical mesh variational autoencoder for shape representation of abdominal organs. Wang Z, Umehara R, Nakamura M, Nakao M. Adv Biomed Eng. in press, 2025
• A prospective study using a spirometry-based system on the positional reproducibility of anatomical landmarks and tumour-tracking accuracy. Kishi N, Matsuo Y, Nakamura M, Ono T, Mukumoto N, Iramina H, Sakurai Y, Matsushita N, Tsuruta Y, Hirashima H, Sasaki M, Fujimoto T, Iizuka Y, Yoshimura M, Mizowaki T. Radiother Oncol. in press, 2025
• Feasibility of markerless real-time tumor tracking volumetric modulated arc therapy using diaphragm-based respiratory offset vectors. Shimizu Y, Kishi N, Mizowaki T, Nakamura M. Med Phys. in press, 2025
• Influence of Applicator Models on Dose Distribution in Gynecologic HDR Brachytherapy. Kishigami Y, Ono T, Matsushita N, Hirashima H, Iramina H, Adachi T, Nakajima A, Tachibana H, Mizowaki T, Nakamura M. Radiol Phys Technol. in press, 2025
• Interfractional shifts of the carina and hilum during radiotherapy for non-small cell lung
  cancer: a retrospective study to identify associated factors. Ueki K, Nakamura M, Araki N. J Appl Clin Med Phys. in press, 2025
• A multi-institutional dummy run on segmentation variability and plan quality of stereotactic body radiotherapy for oligometastatic disease. Hirashima H, Matsuo Y, Ishikura S, Nakamura M, Nishibuchi I, Kawahara D, Shimada Y, Nakahara Y, Nishio T, Shikama N, Watanabe S, Okamoto I, Ishiba T, Hara F, Shien T, Mizowaki T; Lung Cancer Surgical Study Group (LCSSG), the Lung Cancer Study Group (LCSG), Breast Cancer Study Group （BCSG） and Radiation Therapy Study Group (RTSG) of the Japan Clinical Oncology Group (JCOG). Phys Imag Radiat Oncol. in press, 2025
• Multi-Modality Brain Tumor Segmentation using Dual-Attention Generative Adversarial Network. Kawahara D, Nishimura T, Tsuneda M, Okamoto H, Nakamura M, Nishio T, Murakami Y. Rep Pract Oncol Radiother. in press, 2025
• Performance evaluation of second-generation O-ring-shaped image-guided radiotherapy system with a gimbal-mounted linear accelerator and real-time tracking capabilities. Kawata K, Kishigami Y, Hirashima H, Sawada Y, Urago M, Fujimoto T, Fukuda T, Mizowaki T, Nakamura M. J Appl Clin Med Phys. in press, 2025
• Computed tomography-based radiomics prediction of biochemical failure and distant metastasis in patients with high- and very high-risk localized prostate cancer. Adachi T, Hirata K, Aizawa R, Hirashima H, Ogata T, Nakamura M, Mizowaki T. Adv Radiat Oncol. in press, 2025
• Developing reference plans for evaluating global clinical trials credentialing and PSQA systems. Brooks F, Hussein M, Lye J, Nelson CL, Nakamura M, Glenn MC, Diez P, Patel R, Shaw M, Greer P, Patallo IS, Barry M, Olaciregui-Ruiz I, Clark CH, Lehman J, Kry SF. J Appl Clin Med Phys. 26, e70113, 2025
• Dosimetric performance of cone beam CT-guided adaptive carbon-ion radiotherapy with daily replanning for pancreatic cancer. Klassen LF, Hirashima H, Iramina H, Iwai T, Yoshimura M, Tanaka H, Mizowaki T, Nakamura M. Phys Med. 134, 104991, 2025
• Visualization　and　evaluation　of　the　quality　variations　of　EBT4　Gafchromic　film　using　multidimensionals scaling and Lie derivative image analysis. Anetai Y, Tsutsui Y, Kinami S, Yokoi M, Tomita Y, Koike Y, Takegawa H, Doi K, Yoshida K, Nakamura S, Yamada Y, Nakamura M. Phys. Eng. Sci. Med. 48, 797~811, 2025
• A Japanese national survey on IMRT/SBRT in 2023 by the JASTRO High-Precision External Beam Radiotherapy Group. Saito M, Ozawa S, Komiyama T, Kokubo M, Shioyama Y, Matsuo Y, Mizowaki T, Kimura T, Harada H, Igaki H, Tohyama N, Kurooka M, Nakamura M, Kumazaki Y, Suzuki H, Nemoto H, Yasushi N, Onishi H. J Radiat Res. 66, 234~52, 2025
• Integration Test of Biaxially Rotational Dynamic-Radiation Therapy for Nasopharyngeal Carcinoma: Efficacy Evaluation and Dosimetric Analysis. Hiraoka S, Hirashima H, Nakamura M, Tanaka F, Adachi H, Ono Y, Ono T, Nakashima R, Nakajima A, Mizowaki T. Radiother Oncol. 207, 110879, 2025
• Evaluation of intra-fractional anatomical variations during liver MRgART under abdominal compression using optical flow calculation. Adachi T, Mukumoto N, Inokuchi H, Hamaura N, Yamagishi M, Sakagami M, Mukumoto N, Hayashi K, Ogino R, Nakamura M, Shibuya K. Int J Radiat Oncol Biol Phys. 122, 648~58, 2025
• Dummy run study for target delineation and plan quality of intensity-modulated radiotherapy in elderly patients with newly diagnosed glioblastoma: the Japan clinical oncology group study JCOG1910 (AgedGlio-PIII). Ono T, Uto M, Mineharu Y, Arakawa Y, Nakamura M, Nishio T, Igaki H, Nihei K, Ishikura S, Narita Y, Mizowaki T, Brain Tumor Study Group of the Japan Clinical Oncology Group and Radiation Therapy Study Group. Radiat Oncol. 20, 32, 2025
• Margins to compensate for respiratory-induced mismatches between lung tumor and fiducial marker positions using four-dimensional computed tomography. Matsumoto S, Mukumoto N, Ono T, Iramina H, Hirashima H, Adachi T, Miyabe Y, Kishi N, Mizowaki T, Nakamura M. Phys Imag Radiat Oncol. 33, 100728, 2025
• Multi-institutional phase II study on the efficacy and safety of dynamic tumor-tracking, moderately hypofractionated intensity-modulated radiotherapy in patients with locally advanced pancreatic cancer. Yoshimura M, Hiraoka M, Kokubo M, Sakamoto T, Karasawa K, Matsuo Y, Nakamura M, Mukumoto N, Morita S, Mizowaki T. Cancer Med. 14, e70648, 2025
• Patient- and Fraction-specific Magnetic Resonance Volume Reconstruction from Orthogonal Images with Generative Adversarial Networks. Hirashima H, Zhou D, Mukumoto N, Inokuchi H, Hamaura N, Yamagishi M, Sakagami M, Mukumoto N, Nakamura M, Shibuya K. Med Phys. 52, 2785~95, 2025
• Determination of patient-specific trajectory for Biaxially Rotational Dynamic-Radiation Therapy using a new O-ring-shaped image guided radiotherapy system. Hirashima H, Adachi H, Ono T, Nakamura M, Ono Y, Iwai T, Yoshimura M, Mizowaki T. Phys Imag Radiat Oncol. 33, 100698, 2025
• Image-to-Volume Deformable Registration by Learning Displacement Vector Fields. Miura R, Nakamura M, Nakao M. IEEE Trans Radiat Plasma Med Sci. 9, 69~82, 2025

国際学会発表

• Intrafractional Motion Analysis of Pancreatic Tumors and Organs-at-Risk during MRgART Using Optical Flow Calculation. Adachi T, Mukumoto N, Inokuchi H, Hamaura N, Yamagishi M, Sakagami M, Mukumoto N, Hyashi K, Ogino R, Nakamura M, Shibuya S. 67^th ASTRO
• Bayesian Model-Based Internal Target Volume Accounting for Interfractional Hilum Shifts during Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer. Ueki K, Nakamura M, Araki N. 67^th ASTRO
• Application of a conditional diffusion model to improve real-time MR imaging in online adaptive MR-guided radiotherapy. Zhang L, Mukumoto N, Nakao M, Hirashima H, Murahashi N, Inokuchi H, Nakamura M, Shibuya K. 67^th AAPM
• Feasibility of markerless dynamic tumor tracking-VMAT using diaphragm detection and respiratory phase-based offset vector. Shimizu Y, Kishi N, Mizowaki T, Nakamura M. 67^th AAPM
• Deep Learning-Based Multileaf Collimator Sequence Prediction for Automated VMAT Treatment Planning in Pancreatic Cancer. Guan Z, Iwai T, Yoshimura M, Mizowaki T, Nakamura M. 67^th AAPM
• Comprehensive commissioning of an O-ring-shaped image-guided radiotherapy system with a gimbal-mounted linear accelerator. Kishigami Y, Kawata K, Hirashima H, Sawada Y, Urago M, Fukuda T, Mizowaki T, Nakamura M. 67^th AAPM
• Quantification of global dosimetry audit performance: Assessing the sensitivity and specificity of dosimetry audits to establish reciprocity among different international clinical trials credentialing organizations. Brooks F, Lehmann J, Hussein M, Lye J, Nelson CL, Nakamura M, Diez P, Patel R, Greer P, Hirashima H, Larkin JMP, Howell RM, Peterson CB, Clark CH, Kry SF. 67^th AAPM
• Diffusion Model-Based Displacement Field Generation for 4D-CT Chest Image Generation. Kanamuro M, Hirashima H, Nakamura M, Nakao M. 47^th EMBC
• A Multi-domain Model for Reducing Artefacts in Cone-beam CT. Onishi T, Nakamura M, Nakao M, Mizowaki T. ESTRO2025
• Comparison of intra-fractional variations between fiducial marker-based and diaphragm-based registration in lung and pancreatic cancer. Yoneyama M, Iwai T, Adachi T, Kishi N, Nakamura M, Yoshimura M, Mizowaki T. ESTRO2025

招待講演・セミナー・シンポジウム

• 「MR画像がつなぐ分野横断の知」，第53回日本核磁気共鳴医学会大会，中村光宏
• 「適応放射線治療の進化と未来展望」，たちばな放射線治療講演会，中村光宏
• 「Virtual audits – methodology, results and lessons learnt – Japanese experience」，Second Biennial Technical Meeting of the IAEA Dosimetry Audit Network (DAN)，Nakamura M
• 「技術革新が導いた放射線治療の進展と未来への挑戦」，第81回⽇本放射線技術学会総会学術⼤会，中村光宏

受賞

• JRR誌優秀査読者賞，中村 光宏

研究費